Abstract: Lu 2 Block features in high viscosity, great thickness and high permeability. Waterflooding development is adopted in the block. But the water swept area is little, due to the high mobility ratio between injected water and crude oil, high waterline movement velocity, and severe water channeling. As a result, the waterflooding development is influenced considerably. To solve the problem, frothy gel profile control agent is developed, of which the formulation and properties are studied. The profile control agent is used to conduct the deep profile control simulating test and the EOR simulating test in the lab. Test results show that the agent can be frothed in the strata, with the volume three or four times bigger. It can also be forced to the deep strata to form stable and high strength frothy gel, so as to control the profile in deep strata. The agent is suitable to the deep profile control in oil reservoirs with great oil thickness and high permeability, such the Lu 2 Block.