Abstract: With the improvement of directional well drilling teachnique, cluster well drilling technique has been widely accepted in domestic oil fields. It is also conducted in Yan63 Block of Huabei Oilfield based on the geological characteristics. Five-section wellbore track was designed. The area is featured with big amount of wells, large well pattern density, long vertical well section, many well collision factors, and large difficulty of obstacle avoiding during drilling, so it need more requirement for wellbore trajectory control and monitoring. In view of the features above, in the real drilling process, directional profile optimization design and wireless MWD direction and monitoring are used to adjust well trajectory timely, which guarantees the wellbore shape, leading to less eccentric wear in later production. During the drilling process, quick drilling with safety is achieved through optimizing drilling parameters, simplifying drilling tool structure, strictly control trajectory, and optimizing drilling fluid.