Abstract: The current level of horizontal wells fracturing is simply with single well, and the impact of water injection and well patterns are often neglected in enhancing the capacity of single fractured horizontal wells, which appears serious limitations in fracturing effect. Aiming at enhancing the whole block of the recovery, taking the whole reservoir as study object, this paper established an overall fracturing theoretical model for horizontal wells. Fully considering combined distribution of horizontal and vertical wells, a variety of well patterns containing horizontal and vertical wells were designed, and an optimizing design software for horizontal well fracturing was developed. Based on optimizing the well pattern of horizontal wells overall fracturing, considering different length of horizontal sections, the parameters including numbers of fractures, fracture length, conductivity, crack spacing, crack asymmetric distribution and so on were designed, and then the optimal crack parameters have been obtained to forecast the production performance of fractured horizontal wells (daily production, cumulative production, rate of water content, recovery percent of reserves and so on). The method and software would provide certain reference on enhancing the horizontal wells overall fracturing effects.