Abstract: More oil layers developed vertically in Luliang Oilfield, and interlayer interference is more serious, which is affected by oil layer physical property and pressure difference. To further enhance oil recovery and avoid interlayer interference, pump series are developed for separate zone production. Strings for separate zone production, the paraffin removal process and the gauging procedure of are designed successfully. The new technology has been improved continuously and has been used to 20 wells for field test. The oil production increases by 3.2×104 t, and the cycle time of pump inspection is prolonged for more than one year. This technology provides an effective method for the production enhancement of low pressure and low water cut oil layers in the multilayered reservoir.