Abstract: The finite model of tube string vibration on horizontal well was established according to the data of wellbore trajectory,and adopted variable coordinate system to make the tube string displacement along axial orientation and restriction along radial orientation.The tube string of perforated section on horizontal well was vertically loaded by shock wave while it was perforated.The variety relation with time during perforation between axial direction vibration displacement of tube string and velocity was analyzed in detail and obtained that the vertical vibration load of tube string generated by perforation was much more than radial,that was the axial direction vibration took mostly effect.Meanwhile,the variety relation between equivalent stress of tube and time was analyzed and had a conclusion that during the time about 1.0 to 1.5 seconds after perforation the peak equivalent stress value of tube string was generated and sat in deflecting section.It provided the theory data for reasonable designing tube string and how many vibration absorbers were selected.