Abstract: With the development of an oil field, more and more tertiary recovery technologies have been put into field test. Microbe recovery technology has also been made perfectly vecently. The technology is developed from single well gulp and puff to microbe drive, so that it has been a ripe technology. The paper details the microbe drive mechanism, the evaluation of laboratory screening test and the field application result. It is believed that the microbe drive is better than the single well gulp and puff because the previous one has higher sweep efficiency and large treatment area. It has actions in both oil and water wells. The water injecti on offiiency can be improved after a flooding well is treated. The result shows better benefits for operators.