Abstract: The pressure sensitiveness of gas reservoir with low permeability is one of main factors resulting in gas formation damage during drilling. The experimental study was done for the pressure sensitiveness of gas reservoir, by using the rock samples from Shengli Oilfield as standard samples of gas reservoir with low permeability. The experiment indicates that the pressure sensitiveness depends on the size of pressure sensitive point. Pressure delay is found obviously in the gas reservoir. In addition, the pressure sensitiveness of gas reservoir is greater the higher water saturation.