Abstract: The high-efficient viscoelastic profile control and water shutoff agent which applied to plug medium-low permeability reservoirs was developed on the basis of the viscoelastic mechanism of high polymer. The agent can be used to adjust the water injection profile among payzones or in different directions among payzones in order to enhance oil recovery. It has characteristics of good properties and low cost and was applied in some oilfields with the good effect of water control and oil increment. So further popularization and application are needed.