Abstract: The application of guiding drilling system and well trajectory control during drilling process in C-D 1 well were described in this paper. The well with true depth of 2287. 09m, inclination of 58. 4° and displacement of 903. 11m was completed in 15d. The operations of azimuth directioning, angle gain, angle maintaining and angle reduction were accomplished successfully with only one piece of motor, two sets of drill string and three roller bits. The seven targets of the well were shot in one successive operation and the minimum distance from the targets was only 0. 99 m.