Abstract: Screen completion is adopted in the injection and production well XS of Suqiao Underground Gas Storage, and the screen is run into the hole section of 4 900-5 400 m. The reservoir temperature is 160 ℃ and the current pressure coefficient is 0.8. The conventional mechanical diversion and chemical diversion face poor adaptability, high construction difficulty, unsatisfactory plugging effect and other problems. Based on the self-assembly principle of supermolecular chemistry, a kind of liquid temporary plugging and diversion agent was synthesized from lithium chloride, β-cyclodextrin, C₈H₁₇OH, methylcellulose and N-methylformamide. This diversion agent is in the state of liquid under normal temperature. And while the temperature rises to the reservoir temperature, its phase state is liquid, solid and liquid, respectively. The plugging strength, phase change time and fractured core damage degree of the liquid temporary plugging and diversion agent were tested in the laboratory. The experimental results show that this diversion agent has the advantages of easy injection, easy flowback and low damage, effectively solves the problem that diversion technologies are limited under high temperature, long hole section, screen completion and other conditions, and can provide technical support for the temporary plugging, diversion and acid fracturing of special gas wells