Abstract: Offshore oil and gas exploration and development are undergoing a strategic shift to deep and ultra-deep waters. As a critical part of deepwater oil and gas development, deepwater drilling riser will surely be confronted with the major safety problem of vortex induced vibrationg(VIV), and fatigue failure and it is attracting widespread attention. Fluid-structure coupling based on refined flow field simulation with coupled structural dynamic response is an inevitable trend to accurately analyze the VIV characteristics of riser. This paper summarizes some of the research results on numerical simulation during the “Eleventh Five-Year” period and the ongoing research projects in the “Twelfth Five-Year” period. To address the VIV problems of risers in simplified and practical sizes, a high-precision fluid-structure coupling analysis technology is proposed, and reliable physical model, mathematical model and numerical simulation are built for analysis of riser VIV. The comparative experiment verifies the reliability of the models. The large number of numerical simulation researches on the VIV of drilling riser under simplified and practical cases (sea conditions, structure, size, etc.) show the VIV characteristics of riser with practical size under several typical ocean currents with a high reynolds number high under actual sea conditions, such as shear flow, subcritical flow and critical flow, as well as the controlling effect of top tension on the VIV of riser in some way.